Employer: University of Illinois – Chicago
Hiring Department: Pharmacology Practice
Job Title: Postdoctoral Research Associate – Johnson Lab
Additional Information: https://uic.csod.com/ux/ats/careersite/1/home/requisition/6933?c=uic
Our laboratory focuses on the translational development of promising investigational agents. Preclinical studies will focus on evaluating isoprenylated xanthones for the disruption of androgen receptor (AR) functionality for prostate cancer. More specifically, we are interested in promoting degradation of the androgen receptor by small molecules. Our lab environment focuses on a team based model with active collaboration between scientists/fellows in our research group supporting pre-clinical and clinical based projects. Research in our group is supported by NCI (R37, R01, PREVENT), NIH-NICHD, USDA and foundations.
The College of Pharmacy at UIC, with campuses in Chicago and Rockford, is the #1 college of pharmacy in the state of Illinois and the #7 college in the US ranked by US News & World Report. More information about the College and Department of Pharmacy Practice can be found at https://pharmacy.uic.edu and https://dpp.pharmacy.uic.edu
Duties & Responsibilities
Support pre-clinical and clinical studies in oncology/hematology.
Support processing and analysis of patient derived samples to establish molecular phenotypes to support ongoing clinical trials
Conduct animal experiments for this project that include pharmacokinetic evaluation, athymic nude xenografts, and TRAMP mice.
Clinical studies in the UI Cancer Center include evaluating patient derived samples (e.g. plasma, skin, core biopsy) for analysis by qPCR, ELISA, immunoblot.
Possesses and applies comprehensive knowledge of research principles, concepts, practices and methods.
Other duties as assigned.
Perform other related duties and participate in special projects as assigned.
- PhD with training consistent with molecular biology, biomedical sciences or a related discipline.
- A minimum of 1-2 years research experience in molecular biology.
- Displayed proficiency in lab research techniques required.
- The successful candidate will have experience in a laboratory dedicated to translational research in oncology and ideally prostate cancer.
- Attention to detail is essential to support written documentation, present findings, and project report submissions.
- Preference will be given to applicants who demonstrate experience with prostate cancer cell culture (i.e. LNCaP, 22Rv1, VCaP), immunoblot, immunoprecipitation, immunofluorescence microscopy.
- Molecular biology experience with cloning and modifying proteins of interest will be preferred.